Areas
Roppongi/Azabu/Hiroo
Recommended restaurants in this area
You come to this area for Roppongi Hills, Tokyo Midtown, fancy/exclusive restaurants/bars, popular night clubs, established hotels (e.g., Ritz Carlton Tokyo, Grand Hyatt Tokyo). This is the area where you see many non-Japanese people in the streets.
Shibuya/Ebisu/Nakameguro/Daikanyama
Recommended restaurants in this area
Probably, almost all travelers come to check out Shibuya Crossing at least once during their stay in Tokyo. It's the area for young people to hang out. Always crowded.
Shinjuku/Yoyogi
Recommended restaurants in this area
Shinjuku is also popular as a destination for travelers. Lots of skyscrapers and shopping malls. Golden Street (Golden Gai) in the Shinjuku area is now a very popular night spot for non-Japanese travelers.
Harajuku/Omotesando
Recommended restaurants in this area
Like Shibuya, young people come to this area. Crowded all the time. Cafes, clothing stores, nice streets. Meiji Shrine (a must-to-check-out) is located in this area too.
Ginza/Shinbashi
Recommended restaurants in this area
Ginza is an area for 30's and above. Fancy restaurants and bars/clubs. On the other hand, Shinbashi is the area for cheap Izakaya restaurants for middle-aged business people.
Marunouchi/Yaesu
Recommended restaurants in this area
Around Tokyo station. Some good restaurants. Tokyo Imperial Palace is located in this area.
Akasaka/Toranomon/Hibiya
Recommended restaurants in this area
Many Chinese/Korean restaurants are available in this area.
Shinagawa/Meguro/Gotanda
Recommended restaurants in this area
Not must stuff to see in this area. Some quality restaurants, but no other reason to come here for.
Ueno/Asakusa/Akihabara
Recommended restaurants in this area
Asakusa/Ueno is a popular area for tourists for its traditional streets. Some good traditional cuisine restaurants here.
Other areas
Recommended restaurant in the other areas
Other areas than the above. You won't really need to come to these areas unless you want to come for the restaurants.